This study designed to define the significance, status and the patten of change in art in the digital era focuses on the relationship between science technology and visual art. This paper also examines ancient Greek and medieval times when the concept of technology and art had not been differentiated; modern times when art was differentiated from technology and had an independent autonomy as esthetic art; the end of the nineteenth century when technical esthetics originated from diverse trends of modernism and sought for the integration of art and technology. This work discusses the influence of the photography of technical reproduction era on the ways of accommodation and perception of art, based on the insight of Benjamin, who was considered to be the theoretical pioneer of today's media esthetics. In the history of art, when the abstraction of the modernist art movement becomes too extreme, art turns into an objet and transforms into a self-reference from the pursuit of an object. Art goes out of the world of senses which depend on nature, becomes nature itself and is integrated into the world of science and technology. Information art and cyber art will lead to the logical conclusions of technical art which has been dreaming of the integration of art and science and technology. The materiality of object that art pursues will be reduced to non-visual pure abstract logic, will shake the foundation of traditional art and will create changes in the concept and ways of existence of art and the whole art institutions. The intercommunication and the interactivity of the digital media will create esthetic dynamism that the analog media cannot find in art. However, technology determinism that is buried in instrumental convenience should be guarded against. The relationship between human and machine, art and technology will ultimately bring about inevitable diastrophism. Digital media technology that pursues high sophistication and perfection limitlessly expands the horizon of the human perception in virtual space which transcends time and space. However, it can also eliminates critical distance from objet and depletes the imagination and power of meaningful operation that the image itself has.